Who Should Avoid Monolaurin? When to Be Cautious
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Monolaurin &
When to be cautious
About this article:
Learn who should avoid monolaurin and why
Discover interactions with medications and health conditions
Understand safety considerations for kids, seniors, and allergy risks
Get expert-backed guidance before starting monolaurin
Monolaurin is a naturally derived supplement made from lauric acid found in coconut oil. It has gained attention for its antimicrobial properties and possible immune-supportive effects. However, not everyone should take it and those with certain health conditions, life stages, or allergies may need to approach with caution.
In this article, we’ll break down who should avoid monolaurin, what conditions might make it unsafe, and when to talk to your healthcare provider before starting.
Antiviral Evidence: Herpes, Cold Sores & Shingles
Laboratory studies suggest that monolaurin can inactivate lipid-enveloped viruses, including Herpes Simplex Virus types 1 and 2 (HSV-1 and HSV-2), cytomegalovirus, and varicella-zoster virus (which causes shingles).[1][2] As Isaacs et al. (1992) describe, “monoglycerides such as monolaurin cause rapid disintegration of the lipid membranes enveloping certain viruses, leading to loss of infectivity in vitro.” It works in vitro by disrupting the outer layer of the virus, making it less infectious. [Ref #3]
While this sounds promising, these findings are based on lab experiments, not human clinical trials. There is no proven evidence that monolaurin supports herpes or shingles in people. [Ref #2], [Ref #5]
Can Monolaurin Prevent Herpes or Reduce Outbreak Frequency?
Some individuals anecdotally report fewer or milder herpes outbreaks when taking monolaurin as part of an immune-supportive routine. This feedback often comes from long-time users who note changes in outbreak frequency or duration. However, these observations are not supported by peer-reviewed clinical research and should be interpreted with caution.
Although lab research has demonstrated that monolaurin can disrupt the lipid envelope of viruses like HSV and varicella-zoster (which causes shingles), this activity has only been observed in vitro, meaning in lab settings using isolated cells or tissues. [Ref #8]
There are no published clinical trials indicating that monolaurin shortens the healing time of cold sores, reduces blister duration, or decreases symptom severity in people. Some natural health websites claim benefits based on user testimonials or animal models, but these cannot be used to guide medical decisions or safety.
If someone experiences a reduction in duration or severity of viral outbreaks while taking monolaurin, it’s important to remember that correlation is not causation. Many factors, including natural viral cycles and concurrent lifestyle changes, could contribute. Without formal research, claims of faster healing remain unverified
Does It Help Cold Sores or Shingles Heal Faster?
According to Lieberman (1997), “by supporting the body’s innate immune defenses, monolaurin may help maintain normal resistance to common lipid-coated viruses.” Monolaurin may inactivate lipid-enveloped viruses, including herpes simplex, the virus responsible for cold sores—though this finding comes from laboratory studies, not clinical trials. Learn more in Mayo Clinic’s overview of cold sores.
Although research has shown that monolaurin can disrupt the lipid envelope of viruses like HSV and varicella-zoster (which causes shingles), these effects have only been observed in vitro, meaning in controlled lab settings using isolated cells or tissues. [Ref #8]
There are no published human studies indicating that monolaurin shortens cold sore healing time, reduces blister duration, or decreases symptom severity. Some natural health websites cite user testimonials or animal models, but these cannot be relied upon for medical decision-making.
If someone experiences fewer or shorter outbreaks while taking monolaurin, it’s important to note that correlation is not causation. Many factors such as the natural course of the virus, stress levels, and other lifestyle changes may also play a role. Without formal clinical evidence, claims of faster healing remain unverified.
Can It Stop the Virus Completely?
There is no scientific evidence to support the idea that monolaurin can eradicate herpes viruses from the human body. Once a person is infected with HSV-1, HSV-2, or varicella-zoster, the virus migrates to the dorsal root ganglia (clusters of nerve cells) and becomes latent. This means it remains in the body for life, occasionally reactivating under certain conditions such as stress or immune suppression.
Even strong pharmaceutical antivirals do not eliminate the virus entirely; they only manage symptoms and reduce transmission. Monolaurin’s role, if any, is in supporting general immune system function, which may help the body respond more effectively during reactivation episodes.
It's important to avoid overpromising or misunderstanding what monolaurin can achieve. While it may contribute to immune health, it is not a cure for herpes or shingles, and should not replace medically approved treatments when needed.
Who Should Avoid Monolaurin?
Some individuals should avoid monolaurin entirely, while others may need to consult a healthcare provider first.
Can You Take It If You’re Allergic to Coconut?
Monolaurin is typically derived from coconut oil. If you have a known allergy to coconut, avoid monolaurin supplements to prevent adverse reactions. [Ref#2], [Ref#4]
Are There Any Medical Conditions That Make Monolaurin Unsafe?
While generally recognized as safe, people with chronic illnesses, such as:
Kidney or liver disease
Immune disorders
Severe gastrointestinal conditions
...should not take monolaurin without speaking to a healthcare provider. These underlying issues may increase sensitivity to new supplements. [Ref #5], [Ref #6]
Is It Safe for Children?
The Kaplan Clinic notes, “While monolaurin is generally well tolerated in adults, safety data in children remain limited, and use should be approached with caution.” Parents should speak with a pediatrician before considering supplementation for minors.
Should I Take It If I’m on Prescription Medication?
There are no major known drug interactions with monolaurin, but that does not guarantee it's universally safe. If you are taking:
Immunosuppressants
Anticoagulants (blood thinners)
Antiepileptic medications
Hormone therapies
…it’s important to talk to your doctor before starting monolaurin. [Ref#2], [Ref#3]
Even though monolaurin is classified as GRAS (Generally Recognized As Safe), supplements can still interact subtly with medications or affect absorption.
Is It Okay for Kids or Elderly People?
There is limited safety research for monolaurin in both children and older adults:
For children, the developing immune system and differences in metabolism mean supplementation should be supervised by a pediatrician.
For elderly individuals, it’s best to begin with a low dose and adjust slowly under medical oversight especially if managing chronic conditions.
"Monolaurin has not been sufficiently studied in pediatric or immunocompromised populations. Clinical guidance is recommended." Kaplan Clinic
Can I Take Monolaurin with My Medications?
Even though monolaurin does not have many documented interactions, it's wise to speak with your doctor if you're taking any long-term or critical medications. Specific situations where caution is advised:
Chemotherapy or immunotherapy
Autoimmune conditions requiring suppression
Severe liver or kidney dysfunction
Lack of evidence doesn't mean it's universally safe, it just means more research is needed.
Final Thoughts
Monolaurin has shown promising results in laboratory studies, especially in its ability to disrupt the envelope of viruses like herpes and shingles. But until clinical trials in humans confirm those effects, monolaurin should be seen as a supportive wellness tool, not a cure.
You should avoid monolaurin or speak to a healthcare provider first if you:
Have a coconut allergy
Are pregnant or breastfeeding
Are under 12 years old or over 65
Have a chronic illness or take prescription medications
Used responsibly, monolaurin may support immune balance, but always prioritize safety.
Disclaimer: This content is for educational purposes only and not intended to diagnose, treat, cure, or prevent any disease. Monolaurin is a dietary supplement with limited human studies. Always consult a healthcare professional before starting any new supplement, especially if pregnant, breastfeeding, have a medical condition, or take prescription medications. Monolaurin is not a substitute for professional medical treatment.
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References
Lieberman, S., Enig, M. G., & Preuss, H. G. (2006). A review of monolaurin and lauric acid. Altern Complement Ther., 12(6), 310–314. https://doi.org/10.1089/act.2006.12.310
WebMD. (n.d.). Monolaurin: Uses & Side Effects. Retrieved August 10, 2025, from https://www.webmd.com/diet/elderberry-health-benefits
Healthline. (2023). Monolaurin: Benefits, Dosage, and Side Effects. Retrieved August 10, 2025, from https://www.healthline.com/nutrition/monolaurin
Monolaurin and More. (n.d.). Is Monolaurin Safe? Retrieved August 10, 2025, from https://monolaurinandmore.com/safety
RxList. (n.d.). Monolaurin: Benefits, Side Effects, and Interactions. Retrieved August 10, 2025, from https://www.rxlist.com/monolaurin/supplement.htm
Medical News Today. (2022, March 10). Monolaurin: Uses and Precautions. Retrieved August 10, 2025, from https://www.medicalnewstoday.com/articles/monolaurin-benefits
Caring Sunshine. (2021, May 5). Relationship: Herpes and Monolaurin. Retrieved August 10, 2025, from https://www.caringsunshine.com/herpes-monolaurin
PubMed Central. (2023). Clinical Uses of Monolaurin. Retrieved from https://pubmed.ncbi.nlm.nih.gov/
Wikipedia. (2023, June 7). Herpes Simplex Virus. Retrieved from https://en.wikipedia.org/wiki/Herpes_simplex